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Gene-Regulating Proteins Have Drug-Sized Pocket
bHLH-PAS protein family includes proteins involved in cancer, metabolism, and immunity.
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FDA Accepts Novartis NDA for Ribociclib
Novartis LEE011 (ribociclib) granted FDA Priority Review for first-line treatment of HR+/HER2- advanced breast cancer.
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Cause of Inflammation in Diabetes Identified
Suprise discovery has identified a possible trigger of chronic inflammation in diabetes.
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BioStorage Technologies Accelerates Global Sample Management Service Expansion
Expands sample storage services in the U.S. and bioprocessing capabilities in China.
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Quay Pharma, Redx Pharma Collaborate
Collaboration aims to manufacture Redx’s breakthrough cancer treatment drug.
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Alzheimer’s Treatment Moves a Step Closer
Merck scientists have reported the discovery of verubecestat, a structurally unique, orally bioavailable small molecule that has been shown to target the most visible sign of the disease in the brain.
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Adaptimmune, MSD Collaborate
Adaptimmune announces collaboration with MSD to evaluate KEYTRUDA® (pembrolizumab) in combination with NY-ESO SPEAR® T-Cell therapy in multiple myeloma.
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Cannabinoid Receptor Structure Revealed
Scientists provided a detailed view of the primary molecule through which cannabinoids exert their effects on the brain. The findings might help guide the design of more targeted medicines with fewer side effects.
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Uncovering Elusive Proteins
Researchers have determined the complete structure of elusive proteins, known as tetraspanins, for the first time.
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Gene Therapy for Blistering Skin Disease Shows Promise
Grafting genetically altered skin onto patients’ chronic wounds marks the first time skin-based gene therapy has been demonstrated to be safe and effective in humans.
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