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Lung Cancer Drug Cuts Risk of Death by 51% in Clinical Trial

Results of a large Phase 3 clinical trial reveal that a targeted cancer drug, osimertinib, cut the risk of death by 51% for patients following surgery to remove non-small cell lung cancers harboring a specific mutation.
A line graph showing the number of trastuzumab claims in the US by month in 2019-2020.
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Biosimilar Drugs Are Starting To Bring Competition to the Market, Study Finds

The U.S. biosimilar drug market emerged in 2015 to provide safe, effective and more affordable alternatives to existing biologic drugs, but it has been slow to develop compared with Europe.
Montage of a mouse, pill illustrations, agar plates of bacteria and some genome sequencing data with overlaid text.
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How Does the Gut Microbiome Cope With Antibiotics?

It has been unclear how the microbiome responds to repeated antibiotic therapy, but a preclinical study, using metagenome and cultivation analyses, has identified evolutionary mechanisms that contribute to the resilience of the microbial community.
A fruit fly.
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Fruit Flies Could Lead to the Next Antibiotics

Scientists have found that a peptide from fruit flies could lead to new antibiotics.
A molecular visualization showing BTLA being recognized by the antibody LY3361237.
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Study Investigates the Function of Autoimmune Disease Drug Currently in Clinical Trial

Researchers have revealed the structure and function of a drug which can reduce the harmful activity of the immune system to help treat autoimmune diseases, and is currently in a Phase 2 clinical trial for lupus.
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Chest Pain Medication Trial for Hot Flashes Finds Only Short-Lived Benefits

Researchers have found that for menopausal women, continuously wearing a nitroglycerin patch provided short-term improvements in moderate to severe hot flashes but the benefits did not extend past 12 weeks.

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Study Uncovers Mode of Action of New Type 2 Diabetes Drug

Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes.
A psychedelic pattern
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Study Shows How Psychedelic Drugs Rewire the Brain

A new study has revealed details about how the psychedelic drugs LSD and psilocin – the active ingredient in magic mushrooms – bind to receptors in the brain.
A doctor taking liquid up in a needle.
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Clinical Trial Leads to Advances in Treatment for Glioma Patients

In the phase 3 INDIGO clinical trial, vorasidenib significantly prolonged progression free survival and delayed radiation and chemotherapy for patients with Grade 2 IDH-mutant glioma.
Fluorescent imaging of breast cancer cells.
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Immunotherapy Discovery Could Help Prevent Breast Cancer From Spreading

Two new discoveries highlight the different roles of blood vessels in solid tumors – and the findings could help prevent breast cancer from spreading and enhance the effectiveness of one of the most important new cancer treatments in many years.
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