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Drug Delivery System for Chronic Diseases Created Using AI
Researchers implemented AI learning to successfully predict which small proteins can bind to cell structures and delivery drugs in animal models.
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Study Finds Method To Make Glioblastoma Cells "Self-Destruct"
Researchers have developed a method that can kill the aggressive brain tumor glioblastoma in animal models. By blocking certain functions in the cell with a docked molecule, the researchers caused cancer cells to die of stress.
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Promising Results From Small Trial of Drug Combination for Glioblastoma
Improvements in 6-month progression-free survival may warrant additional study in a larger trial.
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Transporter Structure Discovery Sheds Light for Cancer Drug Development
The structure and function of a transporter protein with roles in immunity and cancer have been studied, giving new insights into how it works and how it may be targeted by therapeutics.
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Compound Prevents Kidney Toxicity Caused by Chemotherapy Drug
Researchers in Japan identify a compound that can prevent cisplatin-induced renal toxicity and improve the outcomes of cancer treatment.
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Promising New Stroke Drug Passes Trial Test
A promising new stroke drug that temporarily inhibits a key protein in the brain without causing lasting harm may significantly change the future treatment of cerebral and global ischemia.
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Fast-Aging Mice Live Longer When Oxygen Is Restricted
Massachusetts General Hospital scientists have, for the first time, shown that oxygen restriction increases lifespan in a mouse model of aging. The research is published in PLOS Biology.
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Clinical Trial Found Reduction in Addictive Opioid Painkillers Used for Chronic Pain
Researchers have led a clinical trial on a new treatment which can help people stop needing to use opioid painkillers to manage chronic pain.
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Liver Cancer Is Driven by B Cells
Inflammatory fatty liver disease and the resulting liver cancer are driven by autoaggressive T cells. Scientists now show what is behind this destructive behavior.
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Anti-Nausea Drug Modified To Treat Pain
Altered version of anti-nausea drug netupitant reaches inside cells to disrupt signaling and provide sustained pain relief.
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