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New Method May Help Develop New Drugs Without Side Effects
Researchers discovered a novel method to activate G-protein coupled receptors from inside the cells, and it helps develop drugs without side effects.
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Lung Cancer Drug Cuts Risk of Death by 51% in Clinical Trial
Results of a large Phase 3 clinical trial reveal that a targeted cancer drug, osimertinib, cut the risk of death by 51% for patients following surgery to remove non-small cell lung cancers harboring a specific mutation.
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Biosimilar Drugs Are Starting To Bring Competition to the Market, Study Finds
The U.S. biosimilar drug market emerged in 2015 to provide safe, effective and more affordable alternatives to existing biologic drugs, but it has been slow to develop compared with Europe.
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How Does the Gut Microbiome Cope With Antibiotics?
It has been unclear how the microbiome responds to repeated antibiotic therapy, but a preclinical study, using metagenome and cultivation analyses, has identified evolutionary mechanisms that contribute to the resilience of the microbial community.
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Fruit Flies Could Lead to the Next Antibiotics
Scientists have found that a peptide from fruit flies could lead to new antibiotics.
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Study Investigates the Function of Autoimmune Disease Drug Currently in Clinical Trial
Researchers have revealed the structure and function of a drug which can reduce the harmful activity of the immune system to help treat autoimmune diseases, and is currently in a Phase 2 clinical trial for lupus.
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Chest Pain Medication Trial for Hot Flashes Finds Only Short-Lived Benefits
Researchers have found that for menopausal women, continuously wearing a nitroglycerin patch provided short-term improvements in moderate to severe hot flashes but the benefits did not extend past 12 weeks.
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Study Uncovers Mode of Action of New Type 2 Diabetes Drug
Tirzepatide is a recently approved treatment for type-2 diabetes. Treatment with tirzepatide decreases body weight while improving glucose metabolism in patients with obesity and type-2 diabetes.
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Study Shows How Psychedelic Drugs Rewire the Brain
A new study has revealed details about how the psychedelic drugs LSD and psilocin – the active ingredient in magic mushrooms – bind to receptors in the brain.
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Clinical Trial Leads to Advances in Treatment for Glioma Patients
In the phase 3 INDIGO clinical trial, vorasidenib significantly prolonged progression free survival and delayed radiation and chemotherapy for patients with Grade 2 IDH-mutant glioma.
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