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Small Trial of Cancer-Killing Virus With Immunotherapy Shows Positive Results
Results of a Phase 1/2 clinical trial suggest that oncolytic viral therapy and immunotherapy were safe and improved survival in a subset of patients with recurrent glioblastoma.
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First Humanised Mouse Model Created for Congenital Adrenal Hyperplasia
Mice with a defective human gene responsible for congenital adrenal hyperplasia have been developed for the first time.
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Compound Shows Promise Against Multidrug-Resistant Bacteria
A new peptide has been identified that could be used in the fight against multidrug-resistant bacteria, showing promising results within an hour in laboratory trials.
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New Insights Into Natural Product Biosynthesis Revealed
Single-cell multiomics reveals that cell types are differentially involved in the production and accumulation of medically relevant plant compounds.
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First Human Clinical Trial of Novel Drug To Remove Radioactive Contamination
A first-in-human clinical trial of an experimental oral drug for removing radioactive contaminants from inside the body has begun.
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Brain Region That Could Help Avoid Opioid Relapse Identified
New research has identified the cells and the region of the brain that contribute to opioid relapse, highlighting a potential therapeutic target that may prevent relapse.
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Lack of Oxytocin Proved in People With a Vasopressin Deficiency
Researchers have shown that people with vasopressin deficiency have an oxytocin deficiency as a result of a disease of the pituitary gland.
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Escherichia coli Antibiotic Resistance Tracked in Swine
Researchers have found that since 2013, the number of antimicrobials to which E. coli is resistant has either remained steady or increased over the years.
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High BMI May Reduce the Benefits of Vitamin D Supplements
Vitamin D metabolism is different in people with a BMI greater than 25, which could diminish the effects of vitamin D supplementation, suggests new research from Brigham and Women’s Hospital.
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Study Identifies Mechanisms Underpinning Rapid Antibiotic Resistance
A new study has found that some bacteria can rapidly develop resistance to antibiotics by modifying pumps that remove drugs from the inside of bacterial cells.
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