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Fast-Aging Mice Live Longer When Oxygen Is Restricted
Massachusetts General Hospital scientists have, for the first time, shown that oxygen restriction increases lifespan in a mouse model of aging. The research is published in PLOS Biology.
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Clinical Trial Found Reduction in Addictive Opioid Painkillers Used for Chronic Pain
Researchers have led a clinical trial on a new treatment which can help people stop needing to use opioid painkillers to manage chronic pain.
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Liver Cancer Is Driven by B Cells
Inflammatory fatty liver disease and the resulting liver cancer are driven by autoaggressive T cells. Scientists now show what is behind this destructive behavior.
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Anti-Nausea Drug Modified To Treat Pain
Altered version of anti-nausea drug netupitant reaches inside cells to disrupt signaling and provide sustained pain relief.
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“Zombie” Cells Eliminated With New Molecule
Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to aging. Now, researchers have discovered a new molecule that is able to destroy these old cells without affecting the healthy ones.
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Microbubbles Could Help To Break Bacterial Barriers in Chronic Wound Infections
Researchers have developed a new method to help improve drug delivery in chronic wounds that have been infected with Staphylococcus aureus.
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Chronic Pain Experience Recorded in Patients’ Brains
Scientists from the University of California San Francisco (UCSF) have, for the first time, recorded pain-related data from the brains of patients with chronic pain conditions.
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New Treatment Approach for Rheumatoid Arthritis Shows Promise in Trial
Results of a Phase 2a clinical trial suggest that peresolimab, an antibody that stimulates the human programmed cell death protein 1 (PD-1) pathway, could be a promising new approach for the treatment of rheumatoid arthritis.
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New Drug for Stiff-Heart Syndrome Shows Promise in Small Trial
Transthyretin-related cardiac amyloidosis is a progressive disease characterized by the deposition of amyloid protein fibrils in the heart.
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Huntington’s Disease Symptoms Significantly Reduced by Novel Drug
The drug valbenazine statistically improves chorea, a movement disorder commonly associated with Huntington’s disease, when compared to a placebo, according to a recent international study.
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