APR Acquires Drug Delivery Nanotechnology Platform Providing Treatments for Critical Diseases
News Feb 24, 2009
APR Applied Pharma Research s.a. announces the acquisition of a new platform technology consisting of a patented Nanocoating process for the preparation of new patent protected biotechnology products for the treatment of several critical diseases in multiple therapeutic areas. APR is already developing specific applications of the resulting products in ophthalmology and dermatology. Financial terms of the acquisition were not disclosed.
“We decided to acquire this new platform technology when we understood the great potential of combining a process based on nano-coating technology to totally biological compounds to obtain products with powerful healing capabilities and minimal side effects or tolerability issues” – said Paolo Galfetti, CEO of APR - “The products based on this new technology may unlock new therapeutic solutions to unmet needs in several critical therapeutic areas”.
APR has first targeted the treatment of eye injuries, including cataract, chronic and acute infected wounds, including surgically induced wounds and skin and eye infections, where initial tests made with the first product derived from the new technology showed most promising results. Several other applications of this technology are also being studied.
APR has already performed several “in vitro” and “in vivo” pre-clinical tests studying the critical features of the first product obtained with the nano-coating patented process, including its chemical analysis, stability, toxicology, safety and efficacy with positive and promising results. Also a Phase II study in surgically induced wounds has been performed with excellent results: APR is now ready to enter the first clinical studies in eye wound and cataract healing.
“In order to give the right focus to this new important step in the expansion of APR R&D portfolio as well as to give the Inventors of this technology platform a substantial stake into this venture, APR decided to create a new company specifically dedicated to the development of this and possible future applications of our nanotechnology. This new company, named “APR Nanotechnologies s.a.”, will also be headquartered in Switzerland and will be based in Balerna” – concluded Paolo Galfetti.
Nanoparticles show great promise as diagnostic tools and drug delivery agents. But until now, most nanoparticles had to be injected into the bloodstream because they weren’t absorbed well orally. Now, researchers have modified nanoparticles to improve their uptake in the gastrointestinal tract.