ASINEX and Dompe Announce Successful Collaboration
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DOMPE’ pha.r.ma SpA and ASINEX have announced a project which involved the synthesis and purification of a large targeted orientated library of small molecules using High Throughput Chemistry (HTC) methodology.
The realization of this project was made possible by the close collaboration of DOMPE’ Chemistry Department and ASINEX Computational Departments. A diverse virtual library was generated using a mixture of ASINEX proprietary building blocks and DOMPE’ proprietary synthons. Synthesis and compounds purification were carried out by ASINEX high throughput automated platform.
Dmitry Genis, ASINEX’s CEO said: “Having established an automated platform capable of running 8000 reactions per month and with an ability to purify in HT roughly 8-10K compounds, we can now further expand the broad range of our services including High Throughput Purification and the realization of fast and cost-effective combinatorial libraries on an exclusive basis. The excellent delivery rate indicates the quality and the effectiveness of the library design”.
Gaetano Clavenna, President of Dompé pha.r.ma, commented: The collaboration with ASINEX represents a key step forward in our research programs in the area of allosteric GPCR modulators that surely represents a primary focus for our group. The strong expertise of ASINEX in the field of combinatorial chemistry extraordinarily fits with Dompé pha.r.ma competences and we have great expectations for the results of this project.
