ASINEX and Dompe Announce Successful Collaboration
News May 29, 2007
DOMPE’ pha.r.ma SpA and ASINEX have announced a project which involved the synthesis and purification of a large targeted orientated library of small molecules using High Throughput Chemistry (HTC) methodology.
The realization of this project was made possible by the close collaboration of DOMPE’ Chemistry Department and ASINEX Computational Departments. A diverse virtual library was generated using a mixture of ASINEX proprietary building blocks and DOMPE’ proprietary synthons. Synthesis and compounds purification were carried out by ASINEX high throughput automated platform.
Dmitry Genis, ASINEX’s CEO said: “Having established an automated platform capable of running 8000 reactions per month and with an ability to purify in HT roughly 8-10K compounds, we can now further expand the broad range of our services including High Throughput Purification and the realization of fast and cost-effective combinatorial libraries on an exclusive basis. The excellent delivery rate indicates the quality and the effectiveness of the library design”.
Gaetano Clavenna, President of Dompé pha.r.ma, commented: The collaboration with ASINEX represents a key step forward in our research programs in the area of allosteric GPCR modulators that surely represents a primary focus for our group. The strong expertise of ASINEX in the field of combinatorial chemistry extraordinarily fits with Dompé pha.r.ma competences and we have great expectations for the results of this project.
New Chemical Synthesis Process: Synergy of Two Catalysts in One FlaskNews
Researchers report the one-step synthesis of a ketone from an aldehyde by the combination of thiazolium N-heterocyclic carbene and palladium/bisphosphine catalysts in one flask. The two catalysts function in a synergistic manner. This study is expected to lead to new synthesis processes of precursor compounds for medications.READ MORE
Synthesis of Drug-Like Molecules Simplified Using New Cross-Coupling MethodNews
Researchers have designed a new molecule-building method. The technique, described recently in the journal Science, paves the way toward other new chemical reactions and facilitates the synthesis of pharmaceutically-relevant molecules.READ MORE
Domainex Appoints Dr Bodo Spori as Head of Business Development for EuropeNews
Domainex Ltd, a privately-owned drug discovery services company, is pleased to announce the appointment of Dr Bodo Spori as Head of Business Development for Europe.READ MORE
Comments | 0 ADD COMMENT
Highly Potent Active Pharmaceutical Ingredients (HPAPI)
May 21 - May 22, 2018