BioFocus Launches Four Compound Libraries Targeting Kinases and Protein-protein Interactions
News May 04, 2010
BioFocus’ three new SoftFocus® kinase libraries (SFK61, SFK62 and SFK63) target either the hinge region, allosteric sites or novel binding modes. The SFK collection has been independently determined to have the greatest population of kinase-like molecules available for screening.
BioFocus’ second Helix Mimetic library (HM02) is based on a novel structure that interacts with protein helices. This library is designed to inhibit protein-protein interactions, but can also target other helical recognition motifs such as the pore region of ion channels.
“2010 marks the 11th year of BioFocus’ commitment to producing leading compound libraries for the discovery sector” said Richard Gordon, Senior Director, Sales and Marketing. “Innovative design and compound novelty ensure we provide our clients with the highest chance of success.”
Stereochemistry is a science of reflection. Two chemical molecules with the same composition and structure, but with one as the mirror image of the other, can produce wildly varying effects. But University of Utah chemist Matt Sigman has been developing a way to get a better grasp on this tricky field of chemistry.READ MORE