BioFocus to Host Free Webinar on “Unleashing the Power of Computational Chemistry in Hit Finding Campaigns”
News May 07, 2010
BioFocus invites drug discovery researchers to join its free webinar entitled ‘unleash the power of computational chemistry in hit finding campaigns’, to be held on Thursday 27th May at 15.00 GMT Summer Time. As an educational webinar, attendees will learn how computational chemistry tools enable cost- and time-efficient high-throughput screening (HTS) campaigns.
Topics covered will include: statistical methods to identify more active scaffolds and strengthen the structure-activity relationship (SAR) basis for follow-up activities; structure- and ligand-based compound selection methods; and chemoinformatic tools. Participants will also get the opportunity to view case studies detailing how these approaches facilitate high hit rates, leading to increased success.
New Chemical Synthesis Process: Synergy of Two Catalysts in One FlaskNews
Researchers report the one-step synthesis of a ketone from an aldehyde by the combination of thiazolium N-heterocyclic carbene and palladium/bisphosphine catalysts in one flask. The two catalysts function in a synergistic manner. This study is expected to lead to new synthesis processes of precursor compounds for medications.READ MORE
'Body-on-a-Chip' Could Advance Drug EvaluationNews
MIT engineers have developed new technology that could be used to evaluate new drugs and detect possible side effects before the drugs are tested in humans. Using a microfluidic platform that connects engineered tissues from up to 10 organs, the researchers can accurately replicate human organ interactions for weeks at a time.READ MORE
Hope for Hot Flushes: New Class of Menopause Drugs Reduces SeverityNews
A new class of experimental drugs reduces hot flushes in menopausal women by almost three-quarters in just three days. The new analysis, published in the journal Menopause, also revealed sleep and concentration significantly improved in the three-day window.