Biotage Awarded Patent for Flash Purification Method Development and Optimization
News Apr 21, 2010
Biotage, a manufacturer of automated flash purification, tools and technology for medicinal and analytical chemistry, announced it has recently been awarded U.S. patent 7686959: Control system and Method for Flash Separation.
The patented technology converts thin-layer chromatography (TLC) compound retention data into a linear gradient and also provides the user with sample loading estimates for any Biotage flash cartridge. This novel "TLC-to-Gradient" technology removes all of the trial and error associated with developing flash purification methods.
Recently, Biotage launched related gradient technology for its Isolera flash purification product line. The enhanced gradient optimization (GO) technology can reduce solvent use and cost by 60% or more. With GO technology, results from linear gradients can be purified at a larger scale with an optimized step gradient, which reduces solvent use by as much as 60%. The GO solvent saving feature is available on all new Isolera systems.
Stereochemistry is a science of reflection. Two chemical molecules with the same composition and structure, but with one as the mirror image of the other, can produce wildly varying effects. But University of Utah chemist Matt Sigman has been developing a way to get a better grasp on this tricky field of chemistry.READ MORE