Biotage Awarded Patent for Flash Purification Method Development and Optimization
News Apr 21, 2010
Biotage, a manufacturer of automated flash purification, tools and technology for medicinal and analytical chemistry, announced it has recently been awarded U.S. patent 7686959: Control system and Method for Flash Separation.
The patented technology converts thin-layer chromatography (TLC) compound retention data into a linear gradient and also provides the user with sample loading estimates for any Biotage flash cartridge. This novel "TLC-to-Gradient" technology removes all of the trial and error associated with developing flash purification methods.
Recently, Biotage launched related gradient technology for its Isolera flash purification product line. The enhanced gradient optimization (GO) technology can reduce solvent use and cost by 60% or more. With GO technology, results from linear gradients can be purified at a larger scale with an optimized step gradient, which reduces solvent use by as much as 60%. The GO solvent saving feature is available on all new Isolera systems.
Researchers Develop Novel ‘One-pot’ Approach to Conjugated Tetraenes SynthesisNews
TUAT researchers have achieved the new synthetic route of conjugated tetraenes from inexpensive and easily available 1,3-butadiene and substituted acetylenes by a one-pot approach under mild conditions. Conjugated tetraenes are important key substructures in biologically active natural products such as vitamins, and anti-mycotic drugs.READ MORE
Cancer Fighting Compound Activated by Substance Found in Stinging NettlesNews
Researchers have developed a new line of attack against cancer: an organic-osmium compound, which is triggered using a non-toxic dose of sodium formate, a natural product found in many organisms, including nettles and ants.READ MORE