Breakthrough Approach to Combat Cancer Drug Resistance

News   Feb 09, 2018 | Original story from Maryland University

 
Breakthrough Approach to Combat Cancer Drug Resistance

Overcoming drug resistance by reducing the amount and changing the distribution of P-gp. a Confocal images and fluorescence intensity of P-gp in NCI/RES-ADR multidrug-resistant cancer cells without any treatment (control) and after treated with LSC nanoparticles with laser irradiation (LSC + L, 1 W cm−2 for 1 min). The data show that the P-gp distributes not only on the cell plasma membrane but also in the cytoplasm after the LSC + L treatment, whereas it is dominantly located on the plasma membrane for the cells in the control group. Credit: doi:10.1038/s41467-018-02915-8

 
 
 

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