Cellular Dynamics International Licenses Key Patent Portfolio Surrounding Cardiovascular Progenitor Cells
News Jun 03, 2009
Cellular Dynamics International (CDI) has announced that it has exclusively licensed a key patent portfolio generated by Gordon Keller, Ph.D., previously from Mount Sinai School of Medicine (MSSM), surrounding the differentiation of stem cells into human cardiovascular progenitor cells.
These cells are capable of further differentiation into the multiple cell types of the heart, including cardiomyocytes, endothelial cells, and vascular smooth muscle cells, both in vitro and in vivo.
“The Mount Sinai School of Medicine is pleased that CDI has selected MSSM’s technology for the production and use of cardiomyocytes and other cardiac cells,” said W. Patrick McGrath, Ph.D., Executive Director of MSSM’s Office of Technology and Business Development (OTBD).
“OTBD believes that CDI is well qualified to take the final steps to commercially develop MSSM’s translational research into products and services that will benefit the drug development process and, ultimately, cardiac patients worldwide,” McGrath said.
Commenting on the company’s broadening patent portfolio, Chris Kendrick-Parker, CDI Chief Commercialization Officer, said, “We believe that CDI’s pluripotent stem cell technology will be the pharmaceutical industry’s platform of choice for identifying drug candidates and their probability of success in predictive toxicology. This exclusive license provides CDI complete freedom to operate in our quest to efficiently and effectively produce and provide cardiomyocytes, and other cardiac cells, for screening purposes.”
He continued, “Furthermore, this license strengthens our growing patent portfolio and makes us a preferred collaborator and provider to pharma and biotech companies developing predictive toxicology tools to aid the industry.”
Unraveling How Mesenchymal Stem Cells From Gum Tissue Accelerate Wound HealingNews
To assist with wound healing, mesenchymal stem cells from the gum tissue secrete extracellular vesicles that contain the anti-inflammatory signaling molecule IL-1RA.READ MORE
New Chemical Synthesis Process: Synergy of Two Catalysts in One FlaskNews
Researchers report the one-step synthesis of a ketone from an aldehyde by the combination of thiazolium N-heterocyclic carbene and palladium/bisphosphine catalysts in one flask. The two catalysts function in a synergistic manner. This study is expected to lead to new synthesis processes of precursor compounds for medications.READ MORE
'Body-on-a-Chip' Could Advance Drug EvaluationNews
MIT engineers have developed new technology that could be used to evaluate new drugs and detect possible side effects before the drugs are tested in humans. Using a microfluidic platform that connects engineered tissues from up to 10 organs, the researchers can accurately replicate human organ interactions for weeks at a time.READ MORE