Chemists Design More Efficient Microreactor Using 3D Printing
Researchers from the School of Chemistry at Cardiff University have developed a new way of improving reactions for use in organic chemistry.
The research team around Professor Thomas Wirth developed an electrochemical microreactor using additive manufacturing technology (commonly known as 3D printing). These 3D printed microreactors can be made quickly within a matter of hours, to a variety of designs according to the specifications of the reaction, and at a much lower cost than other microreactors. The use of 3D printing in manufacturing these devices leads to more flexibility as well as higher productivity and efficiency in a large scale laboratory setting.
Traditionally, electrochemical flow microreactors require supporting electrolytes to facilitate reactions. With this new device, very few or no supporting electrolytes are needed, making processes less costly and enabling easier purification of resulting compounds.
The newly developed microreactor was tested on synthesis of isoindolinones, which are found in many natural products, pharmaceuticals, and biologically active molecules, in order to determine the optimum conditions for reactions taking place with the 3D printed microreactor.
The full paper ‘An Easy-to-Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization’ was published in Angewandte Chemie and labelled as a “hot paper” by the editors.
This article has been republished from materials provided by Cardiff University. Note: material may have been edited for length and content. For further information, please contact the cited source.
Protein Target Identified That Could Prevent StrokesNews
Scientists have identified a protein, called GPR68, that senses blood flow and tells small blood vessels called arterioles when to dilate. The researchers believe medications that activate GPR68 could one day be useful to treat medical conditions, including ischemic stroke.READ MORE
Neuropeptide Y Y1 Receptor Structure Solved, Offers New Opportunities for Anti-obesity Drug DiscoveryNews
Scientists solve the crystal structure of Neuropeptide Y Y1 Receptor, offering new opportunities for anti-obesity drug discovery.READ MORE
Crystal Structure of Neuropeptide 1 Receptor Solved, Providing Therapeutic Angle For Obesity TreatmentNews
An international team has uncovered the potential to beat obesity at the cellular level, characterizing for the first time a complex, little-understood receptor type that, when activated, shuts off hunger.READ MORE
Comments | 0 ADD COMMENT
2nd International Conference and Exhibition on Nanomedicine and Drug Delivery
May 21 - May 23, 2018