Debiopharm Group™ Grants Licence for Development, Manufacture and Commercialization of Debio 025
News Feb 10, 2010
Debiopharm Group™ (Debiopharm) has announced the signature of an exclusive licence agreement with Novartis for the development, manufacture and commercialization of Debio 025 (alisporivir), a selective, first-in-class cyclophilin (Cyp) inhibitor with a potent anti-hepatitis C virus (HCV) effect.
The product is currently in phase 2b clinical development for the treatment of hepatitis C. Debiopharm granted Novartis worldwide commercialization rights to Debio 025 except for Japan.
Under the terms of the agreement, Novartis will pay Debiopharm an upfront, development and sales milestones as well as royalties. This transaction is subject to customary regulatory approvals.
According to the World Health Organization 170 million people suffer from HCV in the world. “Sadly only 20% of those patients are treated adequately,” said Rolland-Yves Mauvernay, President and Founder of Debiopharm Group™. “At Debiopharm, we have a strong commitment to providing HCV sufferers with an efficacious cure and are confident about the potential of an innovative, first-in-class compound such as Debio 025, which may represent a breakthrough in the treatment of Hepatitis C. We are very happy to be working alongside Novartis, a partner with a strong dedication to HCV.”
Chinese researchers have developed interfacially polymerized porous polymer particles for low- abundance glycopeptide separation. These polymer particles - with hydrophilic-hydrophobic heterostructured nanopores - can separate low-abundance glycopeptides from complex biological samples with high-abundance background molecules efficiently.