deCODE Initiates Chemical Development Collaboration with SGX
News Jun 15, 2007
deCODE chemistry has initiated a new chemical development service collaboration with SGX Pharmaceuticals. The research performed by deCODE chemistry is aimed at developing and executing a scalable production process for SGX.
Under this collaboration SGX will gain access to deCODE’s platform for chemical development including route optimization, production of toxicology lots, cGMP production of clinical batches, physical form characterization, and all associated analytical method development and validation.
“We are pleased that SGX Pharmaceuticals chose the deCODE chemistry team for their chemical development needs,” said Dr. David Zembower, Vice President of Chemistry at deCODE. “Over the years we have continued to build upon our service platform to provide our valued clients with a rapid, cost-effective transition from selection of development candidates through entry into human clinical trials.”
New Chemical Synthesis Process: Synergy of Two Catalysts in One FlaskNews
Researchers report the one-step synthesis of a ketone from an aldehyde by the combination of thiazolium N-heterocyclic carbene and palladium/bisphosphine catalysts in one flask. The two catalysts function in a synergistic manner. This study is expected to lead to new synthesis processes of precursor compounds for medications.READ MORE
'Body-on-a-Chip' Could Advance Drug EvaluationNews
MIT engineers have developed new technology that could be used to evaluate new drugs and detect possible side effects before the drugs are tested in humans. Using a microfluidic platform that connects engineered tissues from up to 10 organs, the researchers can accurately replicate human organ interactions for weeks at a time.READ MORE
Hope for Hot Flushes: New Class of Menopause Drugs Reduces SeverityNews
A new class of experimental drugs reduces hot flushes in menopausal women by almost three-quarters in just three days. The new analysis, published in the journal Menopause, also revealed sleep and concentration significantly improved in the three-day window.