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Elan and Transition Therapeutics Receive Key Patent for Alzheimer’s Disease Treatment with ELND005

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Elan Corporation , plc and Transition Therapeutics Inc. have announced the United States Patent and Trademark Office issued US patent number 7,521,481 on April 21, 2009. The patent is entitled “Methods of Preventing, Treating and Diagnosing Disorders of Protein Aggregation,” and generally claims methods for treating Alzheimer’s disease comprising administering scyllo-inositol (ELND005). The patent will expire in the year 2025 or later due to any patent term extensions.

“The issuance of this patent is an important milestone in the development of ELND005, a unique oral compound with a favourable safety profile that crosses the blood-brain barrier and targets the disaggregation of amyloid beta in the brain,” said Dr. Tony Cruz, Chairman and Chief Executive Officer of Transition.

In 2006, Elan and Transition entered into an exclusive, worldwide collaboration agreement for the joint development and commercialization of ELND005 for the treatment of Alzheimer’s disease and other indications.