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Embryonic Stem Cells to Treat Eye Disease - ACTC Advanced Cell Technology Files IND with FDA

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Advanced Cell Technology, Inc. has filed an Investigational New Drug (IND) Application with the US Food and Drug Administration (FDA) to initiate a Phase I/II multicenter study using embryonic stem cell derived retinal cells to treat patients with Stargardt’s Macular Dystrophy (SMD).

As many as 10 million people in the United States have photoreceptor degenerative disease. The treatment for eye disease uses stem cells to re-create a type of cell in the retina that supports the photoreceptors needed for vision. These cells, called retinal pigment epithelium (RPE), are often the first to die off in SMD and AMD, which in turn leads to loss of vision.