Enzo Biochem Life Science Unit and BioTek Form Strategic Collaboration
News Oct 20, 2009
Enzo Biochem, Inc. has announced a co-marketing partnership between its Enzo Life Sciences subsidiary and BioTek Instruments.
Aimed at research institutions, as well as biotechnology and pharmaceutical companies, this reagents-instrumentation collaboration creates a highly reproducible and reliable platform for live cell analysis, offering a cost effective alternative to dedicated microplate imaging-based systems, which often are too costly for investigators to implement.
The collaboration will be formally launched next month at MipTec 2009 in Basel, Switzerland with the presentation of the scientific poster, entitled “A cost-effective workflow for high-throughput screening of G-Protein-Coupled Receptors (GPCRs).” The poster details the use of Enzo’s new FluoForte™ Calcium Assay Kit for monitoring intracellular calcium mobilization with BioTek’s Synergy™ Mx Monochromator-based Multi-Mode Microplate Reader.
Drugs targeting GPCRs represent the core of modern medicine, accounting for the majority of the best-selling drugs and roughly 40% of all prescription pharmaceuticals on the market. Using BioTek’s Precision™ XS Automated Sample Processor for all dispensing steps in conjunction with Enzo’s proprietary calcium indicator dye technology and Synergy Mx Microplate Reader provides a small-scale, cost effective, automated cell-based screening approach for identifying GPCR agonists and antagonists. The described assay workflow provides low sample-to-sample variability.
“Through this collaboration, researchers will be able to obtain integrated instrumentation and reagent solutions that are high-performance, yet affordable,“ said Wayne Patton, PhD, Chief Scientific Officer for Enzo Life Sciences. “The collaboration will provide validated turn-key solutions to the research community.”
“Previously, a major source of frustration for many researchers has been that selected assays were not compatible with a particular instrument and vice-versa,” said Peter Banks, PhD, Scientific Director for BioTek Instruments. "Our companies each provide key expertise and capabilities in the live-cell analysis arena bringing together BioTek's capabilities in microplate and dispensing technology that matches perfectly with Enzo’s cutting-edge live cell analysis reagents and kits."
Chinese researchers have developed interfacially polymerized porous polymer particles for low- abundance glycopeptide separation. These polymer particles - with hydrophilic-hydrophobic heterostructured nanopores - can separate low-abundance glycopeptides from complex biological samples with high-abundance background molecules efficiently.