Galapagos Subsidiary BioFocus Collaborate with Senexis
News Dec 02, 2005
Senexis Limited and Galapagos NV have announced that they have expanded their collaboration to optimise Senexis' inhibitors of amyloid-induced toxicity and neuroinflammation for the treatment of Alzheimer's disease.
Galapagos will receive research fees for the medicinal chemistry services provided to Senexis.
The collaboration aims to significantly advance Senexis' small molecule Alzheimer's programs towards the clinic and is unrelated to Galapagos' own Alzheimer's disease targets program.
"We are delighted to continue our successful collaboration with BioFocus," said David Scopes, Senexis' Chief Scientific Officer.
"We have now made significant progress with our small molecule programmes, so that our lead series now demonstrate similar potency to peptides when inhibiting amyloid-induced toxicity."
Onno van de Stolpe, Galapagos' CEO, commented, "We are pleased that BioFocus has been able to help advance Senexis' Alzheimer's program, and offering our medicinal chemistry expertise should further help to accelerate their development program."
Old age is the greatest risk factor for many diseases, including Alzheimer's disease (AD) and cancer. Geroprotectors are a recently identified class of anti-aging compounds. New research has now identified a unique subclass of these compounds, dubbed geroneuroprotectors (GNPs), which are AD drug candidates and slow the aging process in mice.READ MORE