GeneGo and the Cystic Fibrosis Foundation Collaborate to Advance Understanding of Cystic Fibrosis
News Sep 11, 2007
GeneGo, Inc. and the Cystic Fibrosis Foundation have announced their collaboration to develop a software suite for the integration and analysis of cystic fibrosis data. GeneGo's proprietary software combines analytical tools, data content and algorithms for understanding the complex interconnected pathways that are affected in common human diseases.
"We hope this collaboration will better help us to understand the disease and potential therapies at the molecular level," said Robert J. Beall, Ph.D., president and CEO of the Foundation. "Using computational platforms adds to our arsenal of already existing strategies."
The new platform, called MetaMiner (CF), will include off-the-shelf GeneGo products such as MetaCore, MetaDrug, MetaLink and MapEditor. Platforms such as MetaDrug can help to solve various problems including a drug's mechanism of action, toxicity and off-target effects, deduced from the structure and any kind of supplementary omics data.
The product is intended to be used by medicinal chemists and biologists active in pre-clinical areas of high content and high throughput screening, bioassays, hit-to-lead. MetaMiner (CF) will include cystic fibrosis-specific OMICs and small experiments content annotated by GeneGo, disease maps and networks.
"We are very pleased to work with Cystic Fibrosis Foundation and the academic community which is very well organized and successful in research and drug discovery for the disease. We have a clear direction and end goals that we are focused on," said Julie Bryant, GeneGo's vice president of business development.
"This collaboration is the first in the series of disease-centered MetaMiner projects which integrate our existing data analysis tools, OMICs data warehousing and disease-specific knowledge base. We have a dedicated group of Ph.D. and M.D. scientists to work on this project," Bryant said.
The project will be guided by a Cystic Fibrosis Foundation committee with a goal to leverage systems biology technology and accumulated data to advance drug discovery for this disease. MetaMiner (CF) is expected to be available by February of 2008 to cystic fibrosis academic researchers and drug development collaborators through access licenses.
New Chemical Synthesis Process: Synergy of Two Catalysts in One FlaskNews
Researchers report the one-step synthesis of a ketone from an aldehyde by the combination of thiazolium N-heterocyclic carbene and palladium/bisphosphine catalysts in one flask. The two catalysts function in a synergistic manner. This study is expected to lead to new synthesis processes of precursor compounds for medications.READ MORE
Synthesis of Drug-Like Molecules Simplified Using New Cross-Coupling MethodNews
Researchers have designed a new molecule-building method. The technique, described recently in the journal Science, paves the way toward other new chemical reactions and facilitates the synthesis of pharmaceutically-relevant molecules.READ MORE
Domainex Appoints Dr Bodo Spori as Head of Business Development for EuropeNews
Domainex Ltd, a privately-owned drug discovery services company, is pleased to announce the appointment of Dr Bodo Spori as Head of Business Development for Europe.READ MORE
Comments | 0 ADD COMMENT
World Congress on Advanced Pharmacy and Clinical Research
Jul 16 - Jul 17, 2018
6th Annual Congress on Biology and Medicine of Molecules
Sep 17 - Sep 18, 2018