H3 Biomedicine and Selvita Extend Precision Cancer Medicines Collaboration
News Sep 23, 2015
H3 Biomedicine Inc. and Selvita have announced that they have extended their strategic collaboration to develop precision medicines for cancers through September 2016. As part of the original collaboration begun in September 2013, the companies are validating the druggability of two kinase targets in a specific genetic context and have generated multiple novel chemical series against these targets.
The companies are seeking to make further progress towards the initiation of IND enabling studies during 2016. The results from both programs will be presented at scientific conferences in the first half of 2016.
“We are pleased to announce the extension of our collaboration with Selvita. Together we have continued to validate targets within a specific genomic context, which is at the core of H3's vision and mission,” said Markus Warmuth, president and chief executive officer of H3 Biomedicine. “The strength of the combined teams has allowed for rapid advancement of the biology and chemistry in parallel. We look forward to further advancing the programs from discovery to translation over the next year.”
“We are delighted to continue our collaboration with H3. Since the start of our collaboration, our teams have worked very well together, complementing each other’s efforts, said Pawel Przewiezlikowski, chief executive officer of Selvita. The results of both programs have been very promising and we look forward to seeing our jointly discovered molecules progressing through further studies.”
The agreement calls for H3 Biomedicine to provide additional research funding to Selvita, in addition to milestones and royalties on both programs. The financial terms of the agreement are confidential.
Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosisREAD MORE