Horizon Discovery Sign Multi-Year Technology Access Agreement with Genentech
News Dec 24, 2009
Through an additional agreement, Horizon Discovery has provided open access to its 150+ strong X-MAN™ cell-line library to Genentech, Inc., a wholly-owned member of the Roche Group, for a period of up to three years. Genentech will utilize the in-licensed cell-line panels in its oncology research programs. The relationship builds on the previous business agreements between the companies.
X-MAN ‘Mutant And Normal’ cell-lines provide researchers with a consistent source of human cell-types that harbor a specific cancer causing gene (or genes), plus a matched reference normal cell as a control; enabling the rational development of novel drugs or treatments that more effectively target specific patient populations.
Dr Paul Morrill, Business Development Director of Horizon says “Genentech have been a model early-adopter and pivotal to Horizon validating its GENESIS™ and X-MAN technology in an industrial setting. The relationship has yielded some exciting findings which are being translated into publications that will help others striving to develop targeted cancer agents. We believe the new open-access deal with Genentech will further enable Horizon to continue to supply first-in-class, in-vitro models of human cancer for Rx and Dx applications.”
Through its agreements, Genentech pays Horizon undisclosed up-front, milestone and renewal fees.
Protein "Intentionally" Terminates own Synthesis by Destabilizing Synthesis Machinery — the RibosomeNews
A research group has discovered that a protein, during its synthesis, may destabilize the structure of the ribosome and end its own synthesis prematurely, and found that this phenomenon is used for adapting the cell to its environment.READ MORE
Novel Chemistry Technique Simplifies Late-Stage Modification of Drug CompoundsNews
Chemists at The Scripps Research Institute (TSRI) have invented a technique that overcomes a long-standing problem in organic chemistry and should streamline the process of discovery and development for many new drugs.READ MORE