Lab901 to Present at-line Monitoring Solutions at BioProcess International 2010
News May 18, 2010
Lab901 will present their Protein ScreenTape® platform at BioProcess International, which can deliver practical at-line monitoring of monoclonal antibody production.
Prior to the launch of ScreenTape at-line monitoring of antibody production by SDS PAGE has been impractical due to the high cost per test-point and long analysis time.
According to Company, with its rapid staining protocol and automated sample handling, electrophoresis and data presentation, the Protein ScreenTape platform can deliver information on yield, purity and molecular weight within a few minutes. Samples can be analyzed directly from the bioreactor with no need to purify or filter the media. Analysis of media containing high levels of serum is also possible using Protein ScreenTape.
Lab901 application scientist, Adam Inche, said “It is now possible to assess antibody production by SDS-PAGE on a day-by-day, or even hour-by-hour basis, making this information invaluable not only for process optimization, but also for batch monitoring. Using this data our clients will be able to make more informed decisions on when to harvest their bioreaction batch, thereby saving them time and money.”
Scientists have developed a way to identify the beginning of every gene — known as a translation start site or a start codon — in bacterial cell DNA with a single experiment and, through this method, they have shown that an individual gene is capable of coding for more than one protein.