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Malvern Exhibits PAT Solutions for Real-Time Particle Sizing at Interphex 2010

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Interphex, April 20–22 New York, provides an opportunity to learn how PAT (process analytical technology) solutions from Malvern are transforming the control of key unit operations such as milling.

Insitec real-time particle size analyzers deliver a data stream for automated control enabling pharmaceutical manufacturers to achieve consistent product quality, higher throughput and reduced waste.

Also on display will be complementary analytical tools that provide relevant insight across the product cycle. These include Mastersizer, a flexible off-line laser diffraction particle size analyzer, and SyNIRgi, a chemical imaging system that provides information about the spatial location of chemical species within a sample.

In- and on-line Insitec solutions measure full particle size distributions at a rate of up to four per second generating a real-time data stream that promotes a better understanding of powder processing operations. These data also provide a basis for automated control. For manufacture, automated control gives the process the flexibility to maintain product specifications, even when feeds vary, an approach closer to the vision of pharmaceutical manufacture captured in ICH Q8, Q9 and Q10.

The Insitec range includes robust at-, in- and on-line particle sizing solutions that provide 24/7 measurement within the process environment and comply with the stringent requirements of the sector. Maintenance is minimal and reliability extremely high. Technology is available for both wet and dry streams containing particles in the size range 0.1 to 1000 microns.