Medivir Outsources Compound Management to BioAscent
News Aug 23, 2017
BioAscent Discovery Limited has taken delivery of Medivir AB’s compound collection of around 56,000 samples, to manage on an outsourced basis. To ensure business continuity during this transfer process, the complete collection was transferred within three working days, and all compounds were available for delivery to Medivir discovery scientists in less than one week. As well as the existing collection of protease inhibitors and nucleoside analogues, new compounds are being synthesised and delivered to BioAscent each week from Medivir’s CRO partner in India. BioAscent collect and integrate these new compounds into the existing collection and also prepare master stock solutions for Medivir drug discovery activities. Medivir scientists order compounds on a weekly basis and BioAscent supplies them in ready to be tested formats.
BioAscent’s Newhouse facility offers scalable and highly secure infrastructure, capable of managing solid and liquid compounds, in numerous tube and microplate formats, from ambient to -20 °C. Medivir’s compounds are stored as solids or DMSO solutions in master vials within BioAscent’s automated stores at room temperature or -20 oC. Samples to be tested are prepared as requested, and with a turnaround time of just 2.5 working days from receipt of order to delivery to Medivir in Sweden, service time is as fast as when managed in-house by Medivir. BioAscent is also processing and despatching compounds to Medivir research partners in Europe, the USA and Asia.
To manage the complex requirements of its pharma and biotech clients, BioAscent uses Mosaic sample management software as standard. The company has the flexibility to work with other sample management software as required, and Medivir is able to search and order samples held at BioAscent.
Explaining the quick and smooth transfer, Dr Sylviane Boucharens, BioAscent’s COO/CSO, commented: “The BioAscent team is highly experienced at planning the transfer process in meticulous detail, and the Medivir and BioAscent teams combined well to ensure that there was little or no downtime.”
Mr Paul Smith, CEO, BioAscent, added: “The number of companies outsourcing the management of their compound libraries to BioAscent continues to grow apace and we are very pleased to be managing Medivir’s expanding library. Our purpose-built facility near Edinburgh, Scotland is designed for both small and large collections, and we expect to have more announcements in the near future. This continued growth and trust in BioAscent’s world–class facility in Scotland is the perfect platform from which to build our new range of complementary drug discovery services.”
Allergy Amplifier Implicated in Asthma Also Intensifies Food AllergyNews
Scientist who previously reported that a small protein, aptly named histamine-releasing factor, played a pro-inflammatory role in asthma have now shown that it also serves as a “food allergy amplifier”. This work paves the way for blood tests to predict which patients will respond to allergy therapy, and strongly supports the idea that drugs designed to block HRF could prevent food allergy attacks.READ MORE
Researchers Discover Mutation That Appears to Protect Against Multiple Aspects of Biological AgingNews
The first genetic mutation that appears to protect against multiple aspects of biological aging in humans has been discovered in an extended family of Old Order Amish living in the vicinity of Berne, Indiana, report Northwestern Medicine scientists.READ MORE
Discovery of Immune Defense Mechanism Could Help Improve TreatmentsNews
Researchers have identified a previously unknown mechanism by which the responses of key cells of the immune system are regulated. The finding could inform research into improved treatments for allergies or chronic inflammatory diseases.READ MORE