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Molecular Trojan Horse Delivers Chemo Drug to Cancer Cells

News   Feb 26, 2018 | Original story from University of California, Riverside

 
Molecular Trojan Horse Delivers Chemo Drug to Cancer Cells

Schematic illustration of the developed cancer targeting agent -- 123B9 in this study. The compound (right panel) has a scorpion-like shape with two arms grabbing EphA2-expressing cancer cells, and a tail (brown) constituted by a cytotoxic chemotherapeutic agent (paclitaxel used in this work). The agent would recognize the surface of cancer cells rich in EphA2 (labeled in red in the left panel which shows cancer cells) and deliver the cytotoxic agent. Credit: Pellecchia lab, UC Riverside.

 
 
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