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Molecule That Reactivates Dormant Cancer Cells Discovered

Breast cancer cells, with the nucleus shown in blue and microfibers and stress fibers shown in red and green.
Stress Fibers and Microtubules in Human Breast Cancer Cells. Credit: Christina Stuelten, Carole Parent/ National Cancer Institute
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Researchers at Columbia University have found a molecule that is responsible for arousing dormant cells from breast cancer and nudging them to create metastases. Silencing this molecule, called Malat1, in mice with breast cancer reduced metastases and improved survival, suggesting that a similar treatment could benefit patients.

Cancer dormancy