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Neutron Analysis of Glaucoma Drugs Could Help Aggressive Cancer Drug Design

News   Feb 13, 2018 | Original story from Oak Ridge National Laboratory

 
Neutron Analysis of Glaucoma Drugs Could Help Aggressive Cancer Drug Design

This image shows the active site of hCA II. The active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site, based on room-temperature neutron structures. Credit: (ORNL/Andrey Kovalevsky)

 
 
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