Optibrium Joins HeCaToS Project and Expands R&D Team
News Oct 08, 2013
In the course of the project, Optibrium will extend and advance its unique quantum mechanical models that predict metabolism by Cytochrome P450 enzymes, while further developments will focus on predicting the formation of reactive or toxic metabolites. The resulting models will be integrated into the HeCaToS system, to determine if metabolites of new compounds may damage the liver and heart, and support the project’s aim to enable the development of safer medications, cosmetics and industrial chemicals.
The EU is providing twelve million Euros for the project, which is co-ordinated by Maastricht UMC+.
Optibrium has recruited new members to its R&D team to facilitate this project and simultaneously accelerate its software development plans. In particular, to lead its contribution to the HeCaToS project, Optibrium has appointed Dr Patrik Rydberg as Associate Director of Computational Chemistry. Patrik joins Optibrium from the Department of Drug Design and Pharmacology at the University of Copenhagen, where he was Associate Professor. As part of the P450 group in this department, Patrik led the development of the SMARTCyp software and undertook pioneering research on the prediction of metabolism. Patrik will also provide leadership on wider research efforts relating to Optibrium’s StarDrop software, adding his extensive computational chemistry experience to the development of this platform that guides the design and selection of high quality compounds in drug discovery.
Patrik commented, “I am delighted to be joining the Optibrium team and working on the HeCaToS project. This project, with its objective to better predict hepatic and cardiac toxicity, provides an exciting context in which to advance the field of metabolism prediction.”
Cell Recycling System Offers Therapeutic Entry Point for Rare Disease TreatmentNews
Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1).READ MORE
Sysmex Partners with Laboratories to Deliver Improved QC ManagementNews
Sysmex America has announced its latest innovation: a way to make quality assurance easier and more risk free than manual quality control processes.READ MORE
Comments | 0 ADD COMMENT
EMBL Conference: European Conference of Life Science Funders and Foundations
Apr 19 - Apr 20, 2018
EMBL Course: Introduction to Next Generation Sequencing
Apr 09 - Apr 12, 2018
EMBL Course: RNA Sequencing Library Preparation - How Low Can You Go?
Mar 19 - Mar 23, 2018