PharmaDiagnostics is Granted US Patent for Nanoparticle-Conductive Polymer Technology
News Dec 15, 2009
PharmaDiagnostics NV announces that it has been granted a US patent covering its nanoparticle/conductive polymer composites. The patent is entitled "Stable metal/conductive polymer composite colloids and methods for making and using the same".
The company has discovered that, by coating its nanoparticles with a conductive polymer, the inherent sensitivity is increased. This coating enhances the interaction of photons with the electrons on the particles' surface, thus increasing the signal generated when a molecule interacts with the composite. The composites are sensitive to the redox state of the interacting molecules, a physical property of a molecule that is important but often overlooked in the discovery process. The Company uses the technology in its redox potential assay which allows high throughput measurement of redox potential on standard laboratory equipment
Label-free screening is currently an area of great interest in the market. PharmaDiagnostics' approach stands out as all other available label-free technologies require expensive dedicated equipment which restricts both breadth of application and compound throughput.
PharmaDiagnostics' localized surface plasmon resonance technology (LSPR) is broadly enabling, with easy to use protocols, and is applicable to a range of assays for both small molecule and antibody screening and characterization. For the first time, label-free screening can be applied in high throughput applications.
"The grant of this US patent is clear recognition of the innovative nature and industrial applicability of PharmaDiagnostics' technology platform," said Dr David Ricketts, CEO at PharmaDiagnostics. "It is a key step forward for us and will enable us to maximize the commercial potential of our screening technology."
Worms Exhibit Fear and Respond to Anti-anxiety MedsNews
A team of investigators has uncovered new clues about the mechanisms of fear and anxiety through an unlikely creature: the tiny nematode worm.READ MORE
Rechargable Antibacterial Coating - Just Add Bleach!News
Stainless steel is the gold standard for kitchen appliances and cookware, described as modern and sleek. But bacteria can grow on stainless steel surfaces, contaminating food. Current coatings available on the market are pricey and potentially harmful, so scientists have now developed an affordable specialized polymer coating for such surfaces that they can recharge with bleach treatments.READ MORE
Nanotechnology Detects Molecular Biomarker for OsteoarthritisNews
For the first time, scientists have been able to measure a specific molecule indicative of osteoarthritis and a number of other inflammatory diseases using a newly developed technology. This preclinical study used a solid-state nanopore sensor as a tool for the analysis of hyaluronic acid.READ MORE