Sciex, Hepregen Team up on Metabolite Identification Offering
News May 21, 2015
Sciex and Hepregen today announced that they have signed a co-marketing agreement, under which the companies will bundle certain of their technologies together as a metabolite identification (MetID) solution for drug metabolism researchers.
The new offering centers around Hepregen's HepatoPac kit, an in vitro liver model comprising cryopreserved primary hepatocytes from a human, rat, monkey, or dog that are micropatterned onto microwell plates. It also includes Sciex's TripleTOF 6600 LC-MS system, as well as its Swath Acquisition data-capture method and MetabolitePilot software.
Specific terms of the arrangement were not disclosed.
"Until now, particularly in the case of low-turnover compounds, drug metabolism researchers have had significant difficulty predicting in vitro metabolic outcomes with complete confidence," Joe Fox, senior director of Sciex's pharma business, said in a statement. "Together with Hepregen, we have established this much needed end-to-end solution for our MetID customers."
The cholesterol-lowering drugs called statins have demonstrated substantial benefits in reducing the risk of heart attacks and strokes caused by blood clots (ischemic strokes) in at-risk patients. Since statins are associated with a low risk of side effects, the benefits of taking them outweigh the risks, according to a scientific statement from the American Heart Association that reviewed multiple studies evaluating the safety and potential side effects of these drugs.READ MORE
Global Experts Meeting on Frontiers in Biosimilars and Biologics Congress
Oct 24 - Oct 26, 2019