Selvita Signs a Computational Chemistry Services Agreement with IPD, USA
News Apr 06, 2011
Selvita, Poland based integrated discovery partner for the pharmaceutical and biotechnology industry, has announced an agreement with the Institutes for Pharmaceutical Discovery (IPD) in Branford, CT, USA to provide computational chemistry services to IPD.
The aim of this agreement is to identify novel chemical compounds that inhibit the activity of a novel protein target, proposed by IPD. This target protein was selected as the result of a collaboration between IPD and an academic institution, and may be linked to an important class of human diseases.
The compounds identified during this project are expected to demonstrate therapeutic potential as a result of their interaction with the selected protein target. The results of the computational analysis will be experimentally tested in drug discovery research conducted by IPD.
The scope of the project, commissioned to Selvita, includes a druggability study of the targeted protein, followed by a virtual high-throughput screen of structures attainable in public databases, and the interpretation of the “lead-likeness” of the proposed compounds.
“We expect to identify a set of chemical structures possessing the desired characteristics of specific functional inhibitors, with potential therapeutic activity. We are very pleased to be working with Selvita on this novel target,” said Paul Beckett, Senior Director, Synthetic Medicinal Chemistry, at IPD.
"We are very pleased that we can cooperate with The Institutes for Pharmaceutical Discovery,” said Piotr Prelich, Selvita’s VP of Sales and Marketing. “This project is a great chance for Selvita to show the potential of our Computational Chemistry Department. We’ve assembled an excellent team of experienced target modeling and ligand design professionals and I’m sure we can deliver what IPD desires. We’re looking forward to this cooperation very much.”
Many life-saving medicines, including insulin, antibodies and vaccines, are derived from living cells. These “biologics” can be difficult to obtain and store on the battlefield or in remote areas. That’s why scientists are trying to develop portable systems that can quickly manufacture small batches of protein therapeutics on demand.READ MORE
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