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Shire to Attain Enhanced CINRYZE® Manufacturing Flexibility and Capacity
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Shire to Attain Enhanced CINRYZE® Manufacturing Flexibility and Capacity

Shire to Attain Enhanced CINRYZE® Manufacturing Flexibility and Capacity
News

Shire to Attain Enhanced CINRYZE® Manufacturing Flexibility and Capacity

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Shire plc has announced that it has entered into an agreement with Sanquin Blood Supply, the manufacturer of CINRYZE® (C1 esterase inhibitor [human]), providing Shire access to its manufacturing technology and allowing Shire to source additional manufacturers to meet the growing demand for CINRYZE.

“We wanted the freedom to operate and expand in a way that makes strategic sense for our business,” said Flemming Ornskov, M.D., CEO, Shire. “When Shire acquired ViroPharma in January 2014, we inherited an arrangement under which Sanquin was the exclusive manufacturer for CINRYZE. We’re pleased that Sanquin was open to expanding our partnership and agreeing to support us as we increase production options for this important therapy.”

The specific terms of the agreement are confidential, but involve payments to Sanquin on achievement of certain milestones, including a successful technical transfer to a second source manufacturer. Sanquin will continue to serve as a key partner with Shire to increase global supply of CINRYZE.

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