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Sigmoid Enters Into a License Agreement with Pendopharm


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Sigmoid Pharma Limited and Pendopharm have entered into agreements concerning a license for exclusive rights to commercialize CyCol® in the Canadian market and an equity investment in Sigmoid.

Under the license agreement, Sigmoid has received an upfront payment and will be eligible for future milestone payments in addition to significant double-digit, tiered royalties on net sales in Canada. Pursuant to the license agreement, Pendopharm has invested EUR 5 million in Sigmoid at a premium to the most recent fundraising in 2014.

The investment will support the advancement of CyCol® into Phase 3 clinical trials; mainly the scale up of Sigmoid’s manufacturing process for CyCol® and the underlying SmPill® drug delivery technology. David Goodman, CEO of Pharmascience Inc. will join the Sigmoid board of directors.

Dr Ivan S. Coulter, CEO and Founder of Sigmoid, commented: “We are delighted to enter into this important collaboration with Pendopharm. I welcome David to the board and look forward to the expertise and insight he brings. We believe CyCol® has significant potential to treat unmet clinical needs in ulcerative colitis and that Pendopharm, through its existing and growing franchise in the GI therapeutic area, is strongly positioned to maximize the potential of our lead product in Canada. We are confident that this license agreement will be the first of a number of important strategic collaborations to be announced in relation not only to CyCol®, but also to the broadly-applicable SmPill® drug delivery technology.”

Dr David Goodman, CEO of Pharmascience Inc. added: “We are very pleased to be working with Sigmoid to bring CyCol® to Canada. CyCol® is a strategic fit with our GI franchise, and brings another innovative product to the Pendopharm portfolio with attractive therapeutic benefits for patients.”

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