Synthesis and Biological Evaluation of Schiff Bases and Azetidinones of 1-Naphthol
News Sep 04, 2012
Schiff bases and azetidinones form an important structural class possessing wide spectrum of biological activities that include antibacterial and antifungal activity. A series of Schiff's bases N'-(substituted benzylidene)-2-(naphthalen-1-yloxy) acetohydrazides (3a-f) and azetidinones N-[3-chloro-2-oxo-4-(substituted phenyl)-azetidin-1-yl]-2-(naphthalen-1-yloxy) acetamides (4a-b) were synthesized and tested for antimicrobial activity.
This study is punlished online in the Journal of Pharmacy and Bioallied Sciences and is free to access.