Tecan and Pion Expand Collaboration to Develop Automated Drug Screening Solutions
News Jul 16, 2009
Following the launch of the manual assay systems for permeability and solubility, Tecan AG and pION INC have developed automated solutions for drug permeability and solubility screening.
The new automated application provides scalability from an upgradeable, entry-level manual system, to a fully automated system with medium or high throughput, according to changing requirements.
pION’s Double-Sink™ parallel artificial membrane permeability assay (PAMPA), a compound-sparing technique that helps to identify the most promising leads well in advance of cell-based methods, has been integrated with Tecan’s Freedom EVO® platform and Infinite® M200 plate reader in the PAMPA Evolution™.
The system offers enhanced walkaway time and high throughput for fully automated processing of permeability assays, while automated miniaturized shake-flask solubility assays can be done with the similarly configured µSOL Evolution™.
The flexibility of the Freedom EVO workstation also allows the same instrument to perform both permeability and solubility assays in a combined set-up, as well as other ADME assays.
The advanced Quad4 Monochromators™ technology in the Infinite M200 provides sensitivity and an optional MultiChannel Arm™ 96 in the Freedom EVO platform increases throughput with sample transfers.
CRISPR Reveals New Targets for Promising Cancer DrugsNews
Novel screening method identifies new drug targets that could potentially enhance the effectiveness of PD-1 checkpoint inhibitors, a promising new class of cancer immunotherapy.READ MORE
Cell Recycling System Offers Therapeutic Entry Point for Rare Disease TreatmentNews
Scientists have demonstrated how an investigational drug works against a rare, fatal genetic disease, Niemann-Pick type C1 (NPC1).READ MORE
Big-Data Analysis Points Toward New Drug Discovery MethodNews
A research team has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.
Comments | 0 ADD COMMENT
EMBL Conference: European Conference of Life Science Funders and Foundations
Apr 19 - Apr 20, 2018
EMBL Course: Target Engagement in Biology and Drug Discovery
Feb 19 - Feb 23, 2018