The Scripps Research Institute has selected a package of informatics applications from Elsevier MDL to power its research efforts as one of nine institutions chosen to participate in the National Institutes of Health (NIH) Molecular Libraries Screening Centers Network (MLSCN).
Researchers at the Palm Beach County, Florida campus of The Scripps Research Institute will use MDL applications to support high-throughput molecular screening as part of a nationwide collaborative project aimed at accelerating medical discovery.
The Scripps Research Institute will use high-throughput and high-content screening techniques to evaluate small molecules against various biological targets for suitability in developing new treatments for human diseases.
While screening and evaluating pharmacokinetic and toxicological properties, Scripps researchers will utilize a suite of MDL applications, including MDL® Assay Explorer® biological data management system, MDL® ChemBio registration system and MDL® Plate Manager sample and plate management system to capture and analyze the flood of data that comes from those studies.
"Our goal is to identify molecular entities or molecular classes that may have potential benefit for the development of therapeutics by the private sector," said Nick Tsinoremas, Senior Director of Informatics and co-principal investigator for the Scripps Florida screening center. "MDL applications give us a full range of proven informatics capabilities to manage the complex screening we'll employ in this research."
"The suite of MDL applications, selected by Scripps Institute will enable scientists to capture biological and chemical information and integrate it to visualize, analyze and report on experimental data in an advanced collaborative environment," said Jean Colombel, Senior Vice President, Sales and Services, Elsevier MDL. "We're pleased that Elsevier MDL is the principal partner in research informatics for the Scripps Institute Molecular Screening Center and that MDL technology will contribute to the important efforts of the Molecular Library Screening Network."