TTP LabTech Delivers Automated Chemistry System for Salt and Polymorph Screening to AstraZeneca

TTP LabTech announced that it had successfully completed a major laboratory automation project with AstraZeneca. The project, which took over three years to complete, involved the design and build of a fully automated system for salt and polymorph screening of novel compounds.

The system completed its site acceptance test (SAT) late last year before coming on-line at AstraZeneca’s research facility in Sodertalje.

This system for synthesizing and analyzing crystalline materials was designed in partnership between AstraZeneca and TTP LabTech. The overall objectives were to increase throughput, to explore experimental space and to automate the analysis of huge amounts of data.

The project has been undertaken in stages, the first of which was a prototyping stage. This stage helped to minimize risk by tackling those design elements that carried the greatest number of unknowns early in the project.

The next stage was the full design and build of a single screening machine to demonstrate control, functionality, and consistency of the basic automated polymorph screening processes. Now TTP LabTech has been asked to replicate the entire system in order to double the overall throughput.