Latest Posters
Poster
Metabolism of Eight Model Pharmaceutical Compounds in Rat and Human HepatoPac Versus Liver Microsomes and Suspension Hepatocyte Platforms
This poster presents our comparative metabolite profiling analysis of eight model pharmaceutical compounds with various biotransformation reactions using a functionally stable model of primary hepatocytes [micropatterned co-cultures (MPCCs)] in parallel with the traditional liver microsomal and suspension hepatocyte systems.
Poster
Developing a digital histopathology platform to support an international diabetes biobank
An online histopathology platform combines tissue samples and online digital histopathology images. We combine detailed online patient data with whole slide images. This allows potential users of the tissue bank material to select the tissue and patient characteristics before entering into a collaborative agreement. The digital histopathology platform also allows different pathology laboratories in Belgium to discuss histopathological slides, and facilitates research collaboration.
Poster
Recent Technical Developments in the Standardized Separation and Measurement of Extracellular Vesicles
We present robust and practical solutions for the standardization of EV isolation and concentration measurement. EV concentration also needs to have a defined size range. With these solutions, significant improvement in the reproducibility and comparability of results between different researchers is possible.
Poster
Novel Approaches to High-throughput Measurements of Replicative Lifespan in Yeast by Microfluidic Size Sorting and Genetic Engineering
Development of a high-throughput screen utilizing a microfluidic device and a linearly growing yeast strain to simultaneously test the influence of various drugs on the replicative lifespan of yeast.
Poster
Automated Fluorescence Detection and Imaging of RNA Species in Live Cells
This poster describes the detection and quantification of RNA species in Live cells through automated imaging.
Poster
Enabling Epigenetics Studies from HTS to SAR : A Novel HTRF® Platform to Identify and Characterize Reader Domain Inhibitors
Discover a novel HTRF platform to identify and characterize the vast variety of epigenetic binding domain.
Poster
The Longest Way Round is the Shortest Way Home: HTS Assay Development for Complex Multi-domain Protein Kinases
This study strongly supports the possibility to overcome the major bottlenecks in the production of long kinase recombinant forms, in order to perform drug discovery programmes with proteins more closely preserving the structural and functional properties of the native enzymes.
Poster
Identification and Characterisation of Novel Positive Allosteric Modulators of the Galanin 2 Receptor
An HTS against GalR2 was carried out to find novel PAMs to treat neuropathic pain.
Poster
Artificial Multi-Gene Expression Systems Design Service for Natural Compound Formation and Hetero Protein Complexes
Drug discovery of natural compounds drug development and drug target analyses as well as bioproduction can benefit from artificial genetic systems and constructions. The direction in which genes are to be developed is written in the genomes. Synthesis oriented genomic analyses of codon bias and tRNA adaption analyses are prerequisites for generating adaptive, highly functional genes.
Poster
Characterization of Proteins and Protein Self Association (Oligomerization) with SEC-MALS
In this poster, a series of proteins and their oligomers were characterized using SEC-MALS with UV and RI detection. The monomer molecular weights are measured and compared with those from column calibration. The molecular weights of their oligomers are also compared with column calibration and the differences explored.
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