Latest Posters
Poster
Primary Screening of a 1564 Compound Focused Diversity set Against the Human Cardiac Sodium Channel Nav1.5 Using the IonWorks Quattro System
We conducted a feasibility study for using the IonWorks™ Quattro system in a primary screen of a focused library (1564 compounds) for modulators of the cardiac sodium channel Nav1.5 (hH1), an important target for anti-arrhythmia therapeutics.
Poster
High Throughput Automated High Content Screening using a BioCube™ System and Microplate Cytometry
Here, we model the integration of the Protedyne BioCube System and the Acumen Explorer for practical high-throughput, high content screening of protein kinases.
Poster
Diagnostic Genotyping of Drug Metabolising Enzyme Genes on Microarray: The DrugMEt™ Pharmacogenetic IVD Test
A microarray test for in vitro diagnostic use that contains 27 SNPs from 8 different genes with a proven role in the metabolism of major drugs and that may be processed using regular laboratory instrumentation and a range of different scanners.
Poster
Incorporation of Nanolitre Pipetting Technology into Medium and High Throughput SNP Genotyping Platforms at KBiosciences
This poster will describe the current process employed by KBiosciences. The vital role spot-on™ technology, incorporated into the Equator™ benchtop robotic liquid handling instrument, has played in improving performance and reducing costs are highlighted.
Poster
Macrocyclic Library with Conformationally Diverse Scaffold: Synthesis and Biology
Here we present the SIB concept, based on macrocyclic libraries in which the ring size is varied in gradual manner (conformational diversity). This allows selection of bioactive molecules based on their conformational complementary.
Poster
High Throughput Profiling of siRNA and miRNA Libraries using Microplate Cytometry
In this study, we have used microplate cytometry for the phenotypic profiling of both siRNA and miRNA libraries. Data are presented for cell proliferation and cell cycle analysis using propidium iodide nuclear staining and an Acumen Explorer™ laser-scanning fluorescence microplate cytometer.
Poster
Comparison of Fluorescence Lifetime and Fluorescence Intensity Readouts using a Homogeneous Protease-assay
In this work we compare two measurement parameters, the fluorescence intensity (FI) and fluorescence lifetime (FLT), which could be acquired efficiently in a multi parameter readout from one and the same measurement.
Poster
Exploring Reverse Transcription for DNA MicroArrays
Results suggest that random priming is the optimal method for expression analysis of long genes. This method of RT may be appropriate for alternatively spliced genes and for genes without unique probes in the 3’-region.
Poster
Protein Expression Profiling with High-Content Antibody Arrays using Universal Linkage System ULS™ Protein Labeling
The Universal Linkage System (ULS™) is a platinum-based technology that allows direct labeling of proteins and nucleic acids with a large variety of labels and haptens, including many fluorophores, biotin, and dinitrophenol.
Poster
Carbon Nanotubes by Microwave Plasma Enhanced Chemical Vapor Deposition
MICROWAVE Plasma generates radical density characteristic of 2000C at much lower effective temperature and can be highly ionized (Low pressure ECR mode) or highly neutral (high pressure mode).
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