Latest Posters
Poster
Bioluminescent Assay for GTPases Allows Measurement of GTPase, GAP and GEF Activities
We have developed a homogenous bioluminescent assay (GTPase-Glo) system to analyze these proteins in a simple, convenient “add-mix-read” format.
Poster
NanoBRET™ Assays for Monitoring Protein Interactions in Living Cells
Learn how NanoBRET assays can be used to interrogate protein events such as epigenetic interactions, adaptor recruitment to membrane receptors and proteasomal recruitment of proteins targeted for degradation.
Poster
Human iPSC-derived cardiomyocytes: A translational model to predict drug-induced cardiac arrhythmias and long-term toxicity
The results shown here imply that iPSC-derived Cor.4U human cardioymocytes are a translational in vitro cell model for the prediction of clinically relevant drug-induced cardiac arrhythmias and long-term toxicity.
Poster
Lab Reactor – a modular flow reactor
The Lab Reactor is a flow reactor for people that have never done flow chemistry before and wonder where to start.
Poster
Fc Effector Bioassays for Rapid and Quantitative Measurement of ADCC and ADCP Mechanisms of Action
Drug developers are rapidly adopting Fc effector function reporter-based bioassays to measure antibody Fc functions such as ADCC and ADCP activity during the development of therapeutic antibodies. Here we show application of a suite of FcgR Reporter Bioassays to elucidate and characterize antibody MOA.
Poster
Bioluminescent Kinase Profiling Systems for Characterizing Small Molecule Kinase Inhibitors
In order to profile compounds against a broad panel of kinases, in-house profiling requires rigorous kinase assay development.
Poster
Immunotherapy on Chip: “Under the Microscope” Drug-induced Modulation of the Immune Response
The immune system is a striking example of an integrated information system, engaged in coordinated host-protective activities. Organs-on-chip approach (OOC) models allow the direct simultaneous observation of hundreds of different cells, moving, interacting and responding to signals coming from the microenvironment nearby, that give access to a number of parameters describing the system that must be properly measured and elaborated.
Poster
Characterizing GPCR Activation Using Automated Live Cell Imaging
Here we describe a live cell imaging based approach to detect GPCR activation using the Lionheart™ FX Automated Live Cell Imager and Gen5™ Microplate Reader and Imager Software.
Poster
Assessment of Oral LISPRO Treatment in Ameliorating Amyloid and Tau Pathology in Transgenic Alzheimer’s Mice Model
Ionic co-crystals of lithium salicylate with organic proline (LISPRO) showed better safety and pharmacokinetic profile of lithium in plasma and brain of wild-type and transgenic Alzheimer mice model compared to lithium salts.
Poster
Determination of the Fat Content Profile of different Chocolate Products using an Automated Workflow for the Generation of Fatty Acid Methyl Esters (FAME)
The method allows for automated determination of total fat content and quantitative analysis of saturated and unsaturated cis- and trans- fatty acids of different chocolate products.
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