Combinatorial synthesis of oxazolidin-2-ones using Fmoc-Ser(Trt)-OH, a library with high degree of diversity
Published: February 25, 2008
A library of oxazolidin-2-ones was prepared by solid phase synthesis. Crutial reaction steps were optimized. Highly divers building blocks were selected for the synthesis. All compounds were purified using preparative LC/MS with mass directed fraction collection.