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EM Algorithm for Gene Copy Number Estimation Using TaqMan® Assays

EM Algorithm for Gene Copy Number Estimation Using TaqMan® Assays content piece image
Abstract
Recently, TaqMan® assays have been developed for detection of genetic variation at gene level using primers and probes designed for genomic DNA sequences. The R package TaqGCN contains classes and methods that can be used for data reading and plotting, and for predicting gene copy number.