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Drug Discovery

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Evaluation of Human Regional Bioavailability to Assess Whether Modified Release Development is Feasible

Poster

Published: June 19, 2008

Evaluation of Human Regional Bioavailability to Assess Whether Modified Release Development is Feasible content piece image

Many modified release (MR) oral formulations rely on bioavailability from the distal regions of the gastrointestinal (GI) tract (i.e. the ileum and colon). Therefore, by assessing the bioavailability of a drug following delivery to the distal intestines, it is possible to determine whether MR formulation development is achievable.