Poster May 05, 2011
Chris de Graaf, Gerdien de Kloe, Henry Vischer, Mark Verheij, Saskia Nijmeijer, Azra Delic, David Maussang, Ken Chow, Anitha Shanmugham, Paul England, Rogier Smits, Rob Leurs and Iwan de Esch
The poster demonstrates the following:
• All screens have resulted in unique and novel fragment hits.
• The use of fragments in chemogenomics approaches results in higher resolution interaction fingerprints and leads to improved structural understanding and novel insights in ligand binding characteristics.
• These studies can support the design of novel ligands with specified activity profiles.
CiPA Phase 2 Study: validation of an automated microelectrode array (MEA) assay of hiPSC-derived cardiomyocyte electrophysiology for cardiac safety evaluationPoster
These results support the use of hSC-CM and MEA technology for preclinical assessment of proarrhythmic risk within the proposed CiPA paradigm, and, more generally, demonstrate that automation of the CM-MEA assay can achieve high reliability and throughput for cardiac risk assessment in vitro.READ MORE
A luminescent solar concentrator-based photomicroreactor for energy efficient continuous-flow photocatalysisPoster
The Luminescent Solar ConcentratorPhotomicroreactor
(LSC-PM) is an innovative device
for solar-powered continuous-flow photochemistry.
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Orphan Drugs and Rare Diseases Global Congress 2017 USA
Sep 12 - Sep 14, 2017