High-Throughput Analysis of DNA Samples using the D1K ScreenTape Assay and the Agilent 2200 TapeStation System
Poster Nov 05, 2012
Arunkumar Padmanaban, Ruediger Salowsky, Adam Inche
Recent advances in genomics demands to look at a wealth of genetic information in a short period of time. DNA analysis using slab gel electrophoresis and capillary electrophoresis are widely being used as a QC step in next generation sequencing and microarray studies. However, often these techniques lack the speed and involve more manual steps to perform the assay. The Agilent 2200 TapeStation system meets this demand by providing a simple to use automated electrophoresis platform with variable throughput capabilities from one or two samples up to a 96-well plate. The Agilent 2200 TapeStation system along with the D1K ScreenTape assay can analyze a full 96-well plate in less than 100 minutes with minimal manual intervention.
Complete “Sample-to-Result” Highly Automated NGS and qPCR Workflow for Clinical DiagnosticsPoster
Complete “Sample-to-Result” Highly Automated NGS and qPCR Workflow for Clinical Diagnostics.READ MORE
Inhibition of The Auto-inflammation Suppressor Protein ISG15 Triggers Preeclampsia by Blocking Trophoblast Migration and InvasionPoster
In summary, ISG15 expression levels are crucial for trophoblast morphology and function (migration/invasion). By blocking trophoblast invasion, reduced ISG15 levels could contribute to impaired spiral artery transformation that reduces utero-placental blood flow in preeclampsia. Thus, agents inducing ISG15 expression are likely to be therapeutic in preeclampsia.
An Emerging Phenotype of Partial RAG 1/2 Deficiency Among Young Children with Autoimmunity and Viral InfectionsPoster
We describe the natural history of a cohort of 12 patients with confirmed partial RAG1/2 mutations and autoimmunity at a young age. We were seeking the link between viral infections and autoimmunity and tested candidate biomarkers that may reflect the underlying RAG1/2 protein deficiency.READ MORE