Initiatives For The Sharing Of Toxicity Data
Poster Oct 30, 2007
Much high-quality toxicity information is held within organisations rather than being in the public domain. Organisations would benefit from sharing this data with each other in a reciprocal manner where commercial sensitivity issues allow. Vitic, a structure-searchable toxicity database, has recently been used as the basis for a number of such data sharing initiatives. Consortia include those interested in the sharing of toxicity data on intermediates and impurities.
During early drug discovery, the study of metabolism plays an essential role in determining which drug candidates move forward into development and later stages. As an alternative to traditional Data Dependent Acquisition (DDA), the use of MSE/All Ions Fragmentation (AIF) has become common in metabolite identification workflows for the analysis of metabolic hot spots. Here we present a solution for analysis of MSE/AlF in metID studies.READ MORE