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Involvement of enkephalins and delta-opioid receptors in the expression of levodopa-induced dyskinesia in a model of hemiparkinsonian rat

Poster   Apr 02, 2008

 
Involvement of enkephalins and delta-opioid receptors in the expression of levodopa-induced dyskinesia in a model of hemiparkinsonian rat
 
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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License

 
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Anti-CelTOS Transmission Blocking Activity in vivo and in vitro against P. falciparum by Epitope-specific Monoclonal Antibodies

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The presence of CelTOS mAb significantly inhibited oocyst development in mosquitoes in both in vivo and in vitro assays. Importantly, the experimental results with an innovative in vivo humanized mouse model confirmed that circulating anti-CelTOS antibody effectively inhibits P. falciparum ookinete development to oocyst in mosquitoes. These results support the development of CelTOS as a transmission blocking vaccine.

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