Isothermal Titration Microcalorimetry: An Essential Tool for Fragment-Based Drug Discovery
Isothermal titration microcalorimetry (ITC) is an essential tool in drug discovery, enabling researchers to study and regulate protein interactions. Recent advancements in ITC instrumentation have led to an increase in the throughput and decrease in the protein consumption of the technique. When combined with the extended affinity range, these factors make the technique ideal for fragment-based drug discovery campaigns.
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